February 23, 2025

Notre Dame vs. Ohio State picks, predictions: Who wins Week 1 college football game?


Show Caption Hide Caption Why Notre Dame is so much better off without Brian Kelly FTW college football writers Michelle Martinelli and Caroline Darney debate the current and future state of Notre Dame. USA TODAY The No. 2 Ohio State Buckeyes host the No. 5 Notre Dame Fighting Irish Saturday in a Week 1 college football game between Top 5 teams. Which team will win the game? Check out these picks and predictions for the game, which is scheduled to begin at 4:30 p.m. MST and can be seen on ABC. Ohio State football is a 16.5-point favorite in the game, according to Tipico Sportsbook. College football Week 1 picks, predictions: Pete Fiutak writes: “The Irish defense should be able to hold on better than many might think. Ohio State will win – the D really will be better – but it’ll take a little while before the dam breaks.…

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